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Stem Cell Strategies to Evaluate Idiosyncratic Drug-induced Liver Injury
The host-dependent nature of idiosyncratic drug-induced liver injury (iDILI) suggests that rare genetic polymorphisms may contribute to the disease. Indeed, a few mutations in key genes have already been identified using conventional human genetics approaches. Over 50 commonly used drugs can precipi...
Autores principales: | Krueger, Winfried, Boelsterli, Urs A., Rasmussen, Theodore P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
XIA & HE Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521249/ https://www.ncbi.nlm.nih.gov/pubmed/26355943 http://dx.doi.org/10.14218/JCTH.2014.00012 |
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