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Pathology of Alcoholic Liver Disease
Alcohol-attributable burden on global health is increasing, and the relationship between population alcohol consumption and liver-related deaths is strong. Longstanding scientific and clinical work has led to a relatively thorough, if not complete, understanding of the effects of alcohol consumption...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
XIA & HE Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521259/ https://www.ncbi.nlm.nih.gov/pubmed/26357621 http://dx.doi.org/10.14218/JCTH.2014.00010 |
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author | Celli, Romulo Zhang, Xuchen |
author_facet | Celli, Romulo Zhang, Xuchen |
author_sort | Celli, Romulo |
collection | PubMed |
description | Alcohol-attributable burden on global health is increasing, and the relationship between population alcohol consumption and liver-related deaths is strong. Longstanding scientific and clinical work has led to a relatively thorough, if not complete, understanding of the effects of alcohol consumption on the liver. Pathologic features of alcoholic liver disease (ALD) are recognized by pathologists and used to assist clinicians in diagnosing and determining severity of disease in patients suspected of ALD. In this review, we discuss the pathologic manifestations of ALD and provide salient points on their pathophysiology. In addition, the benefits and indications of liver biopsy and important differential diagnoses, including features distinguishing these entities, are reviewed. |
format | Online Article Text |
id | pubmed-4521259 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | XIA & HE Publishing Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-45212592015-09-09 Pathology of Alcoholic Liver Disease Celli, Romulo Zhang, Xuchen J Clin Transl Hepatol Review Article Alcohol-attributable burden on global health is increasing, and the relationship between population alcohol consumption and liver-related deaths is strong. Longstanding scientific and clinical work has led to a relatively thorough, if not complete, understanding of the effects of alcohol consumption on the liver. Pathologic features of alcoholic liver disease (ALD) are recognized by pathologists and used to assist clinicians in diagnosing and determining severity of disease in patients suspected of ALD. In this review, we discuss the pathologic manifestations of ALD and provide salient points on their pathophysiology. In addition, the benefits and indications of liver biopsy and important differential diagnoses, including features distinguishing these entities, are reviewed. XIA & HE Publishing Ltd 2014-06-15 2014-06 /pmc/articles/PMC4521259/ /pubmed/26357621 http://dx.doi.org/10.14218/JCTH.2014.00010 Text en © 2014 The Second Affiliated Hospital of Chongqing Medical University. Published by XIA & HE Publishing Ltd. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 4.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Celli, Romulo Zhang, Xuchen Pathology of Alcoholic Liver Disease |
title | Pathology of Alcoholic Liver Disease |
title_full | Pathology of Alcoholic Liver Disease |
title_fullStr | Pathology of Alcoholic Liver Disease |
title_full_unstemmed | Pathology of Alcoholic Liver Disease |
title_short | Pathology of Alcoholic Liver Disease |
title_sort | pathology of alcoholic liver disease |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521259/ https://www.ncbi.nlm.nih.gov/pubmed/26357621 http://dx.doi.org/10.14218/JCTH.2014.00010 |
work_keys_str_mv | AT celliromulo pathologyofalcoholicliverdisease AT zhangxuchen pathologyofalcoholicliverdisease |