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Synergy Maps: exploring compound combinations using network-based visualization

BACKGROUND: The phenomenon of super-additivity of biological response to compounds applied jointly, termed synergy, has the potential to provide many therapeutic benefits. Therefore, high throughput screening of compound combinations has recently received a great deal of attention. Large compound li...

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Detalles Bibliográficos
Autores principales: Lewis, Richard, Guha, Rajarshi, Korcsmaros, Tamás, Bender, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521339/
https://www.ncbi.nlm.nih.gov/pubmed/26236402
http://dx.doi.org/10.1186/s13321-015-0090-6