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Analyzing allele specific RNA expression using mixture models

BACKGROUND: Measuring allele-specific RNA expression provides valuable insights into cis-acting genetic and epigenetic regulation of gene expression. Widespread adoption of high-throughput sequencing technologies for studying RNA expression (RNA-Seq) permits measurement of allelic RNA expression imb...

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Detalles Bibliográficos
Autores principales:	Lu, Rong, Smith, Ryan M, Seweryn, Michal, Wang, Danxin, Hartmann, Katherine, Webb, Amy, Sadee, Wolfgang, Rempala, Grzegorz A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521363/ https://www.ncbi.nlm.nih.gov/pubmed/26231172 http://dx.doi.org/10.1186/s12864-015-1749-0

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