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dissectHMMER: a HMMER-based score dissection framework that statistically evaluates fold-critical sequence segments for domain fold similarity
BACKGROUND: Annotation transfer for function and structure within the sequence homology concept essentially requires protein sequence similarity for the secondary structural blocks forming the fold of a protein. A simplistic similarity approach in the case of non-globular segments (coiled coils, low...
Autores principales: | Wong, Wing-Cheong, Yap, Choon-Kong, Eisenhaber, Birgit, Eisenhaber, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521371/ https://www.ncbi.nlm.nih.gov/pubmed/26228544 http://dx.doi.org/10.1186/s13062-015-0068-3 |
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