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Dynamic single cell measurements of kinase activity by synthetic kinase activity relocation sensors

BACKGROUND: Mitogen activated protein kinases (MAPK) play an essential role in integrating extra-cellular signals and intra-cellular cues to allow cells to grow, adapt to stresses, or undergo apoptosis. Budding yeast serves as a powerful system to understand the fundamental regulatory mechanisms tha...

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Detalles Bibliográficos
Autores principales: Durandau, Eric, Aymoz, Delphine, Pelet, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521377/
https://www.ncbi.nlm.nih.gov/pubmed/26231587
http://dx.doi.org/10.1186/s12915-015-0163-z