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Generation of stable ARE- driven reporter system for monitoring oxidative stress

BACKGROUND: NF-E2-related factor2 (Nrf2)-antioxidant response element (ARE) signaling pathway is the major defensive mechanism against oxidative stress and is up regulated by specific antioxidants and oxidants to comprise the chemoptotective response. Detection of ARE-activating compounds helps to d...

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Detalles Bibliográficos
Autores principales: Motahari, Paria, Sadeghizadeh, Majid, Behmanesh, Mehrdad, Sabri, Shaghayegh, Zolghadr, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521422/
https://www.ncbi.nlm.nih.gov/pubmed/26231224
http://dx.doi.org/10.1186/s40199-015-0122-9