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High-level expression of human arginase I in Pichia pastoris and its immobilization on chitosan to produce L-ornithine

BACKGROUND: L-ornithine (L-Orn), is an intermediate metabolite in the urea cycle that plays a significant role in humans. L-Orn can be obtained from the catalysis of L-arginine (L-Arg) by arginase. The Pichia pastoris expression system offers the possibility of generating a large amount of recombina...

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Detalles Bibliográficos
Autores principales: Zhang, Xue, Liu, Jin, Yu, Xianhong, Wang, Fei, Yi, Li, Li, Zhezhe, Liu, Yunyun, Ma, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521451/
https://www.ncbi.nlm.nih.gov/pubmed/26227111
http://dx.doi.org/10.1186/s12896-015-0184-2