Cargando…

A case of methyl ethyl ketone peroxide poisoning and a review of complications and their management

Methyl Ethyl Ketone Peroxide (MEKP) is a highly toxic clear liquid used as a solvent. It is a strong oxidizing agent and a corrosive. Acute and chronic toxicity can occur as an occupational hazard. Ingestion is associated with corrosive burns leading to stricture formation, inhalational pneumonitis,...

Descripción completa

Detalles Bibliográficos
Autores principales: Liyanage, Isurujith K., Navinan, Mitrakrishnan R., Pathirana, A C A, Herath, H R I S, Yudhishdran, Jevon, Fernandopulle, Nilesh, Kulatunga, Aruna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521457/
https://www.ncbi.nlm.nih.gov/pubmed/26236387
http://dx.doi.org/10.1186/s12995-015-0071-8
_version_ 1782383812599087104
author Liyanage, Isurujith K.
Navinan, Mitrakrishnan R.
Pathirana, A C A
Herath, H R I S
Yudhishdran, Jevon
Fernandopulle, Nilesh
Kulatunga, Aruna
author_facet Liyanage, Isurujith K.
Navinan, Mitrakrishnan R.
Pathirana, A C A
Herath, H R I S
Yudhishdran, Jevon
Fernandopulle, Nilesh
Kulatunga, Aruna
author_sort Liyanage, Isurujith K.
collection PubMed
description Methyl Ethyl Ketone Peroxide (MEKP) is a highly toxic clear liquid used as a solvent. It is a strong oxidizing agent and a corrosive. Acute and chronic toxicity can occur as an occupational hazard. Ingestion is associated with corrosive burns leading to stricture formation, inhalational pneumonitis, acidosis, liver failure and renal failure. In this paper we present a case of a young patient who intentionally ingested MEKP. The patient developed multiple complications including proximal intestinal obstruction, acidosis and acute kidney injury. He was managed conservatively and recovered after a prolonged hospital stay. He had multiple inflammatory strictures on esophageal endoscopy, which improved over 3–6 moths.
format Online
Article
Text
id pubmed-4521457
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-45214572015-08-01 A case of methyl ethyl ketone peroxide poisoning and a review of complications and their management Liyanage, Isurujith K. Navinan, Mitrakrishnan R. Pathirana, A C A Herath, H R I S Yudhishdran, Jevon Fernandopulle, Nilesh Kulatunga, Aruna J Occup Med Toxicol Case Report Methyl Ethyl Ketone Peroxide (MEKP) is a highly toxic clear liquid used as a solvent. It is a strong oxidizing agent and a corrosive. Acute and chronic toxicity can occur as an occupational hazard. Ingestion is associated with corrosive burns leading to stricture formation, inhalational pneumonitis, acidosis, liver failure and renal failure. In this paper we present a case of a young patient who intentionally ingested MEKP. The patient developed multiple complications including proximal intestinal obstruction, acidosis and acute kidney injury. He was managed conservatively and recovered after a prolonged hospital stay. He had multiple inflammatory strictures on esophageal endoscopy, which improved over 3–6 moths. BioMed Central 2015-07-31 /pmc/articles/PMC4521457/ /pubmed/26236387 http://dx.doi.org/10.1186/s12995-015-0071-8 Text en © Liyanage et al. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Liyanage, Isurujith K.
Navinan, Mitrakrishnan R.
Pathirana, A C A
Herath, H R I S
Yudhishdran, Jevon
Fernandopulle, Nilesh
Kulatunga, Aruna
A case of methyl ethyl ketone peroxide poisoning and a review of complications and their management
title A case of methyl ethyl ketone peroxide poisoning and a review of complications and their management
title_full A case of methyl ethyl ketone peroxide poisoning and a review of complications and their management
title_fullStr A case of methyl ethyl ketone peroxide poisoning and a review of complications and their management
title_full_unstemmed A case of methyl ethyl ketone peroxide poisoning and a review of complications and their management
title_short A case of methyl ethyl ketone peroxide poisoning and a review of complications and their management
title_sort case of methyl ethyl ketone peroxide poisoning and a review of complications and their management
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521457/
https://www.ncbi.nlm.nih.gov/pubmed/26236387
http://dx.doi.org/10.1186/s12995-015-0071-8
work_keys_str_mv AT liyanageisurujithk acaseofmethylethylketoneperoxidepoisoningandareviewofcomplicationsandtheirmanagement
AT navinanmitrakrishnanr acaseofmethylethylketoneperoxidepoisoningandareviewofcomplicationsandtheirmanagement
AT pathiranaaca acaseofmethylethylketoneperoxidepoisoningandareviewofcomplicationsandtheirmanagement
AT herathhris acaseofmethylethylketoneperoxidepoisoningandareviewofcomplicationsandtheirmanagement
AT yudhishdranjevon acaseofmethylethylketoneperoxidepoisoningandareviewofcomplicationsandtheirmanagement
AT fernandopullenilesh acaseofmethylethylketoneperoxidepoisoningandareviewofcomplicationsandtheirmanagement
AT kulatungaaruna acaseofmethylethylketoneperoxidepoisoningandareviewofcomplicationsandtheirmanagement
AT liyanageisurujithk caseofmethylethylketoneperoxidepoisoningandareviewofcomplicationsandtheirmanagement
AT navinanmitrakrishnanr caseofmethylethylketoneperoxidepoisoningandareviewofcomplicationsandtheirmanagement
AT pathiranaaca caseofmethylethylketoneperoxidepoisoningandareviewofcomplicationsandtheirmanagement
AT herathhris caseofmethylethylketoneperoxidepoisoningandareviewofcomplicationsandtheirmanagement
AT yudhishdranjevon caseofmethylethylketoneperoxidepoisoningandareviewofcomplicationsandtheirmanagement
AT fernandopullenilesh caseofmethylethylketoneperoxidepoisoningandareviewofcomplicationsandtheirmanagement
AT kulatungaaruna caseofmethylethylketoneperoxidepoisoningandareviewofcomplicationsandtheirmanagement