AduPARE1A and gemcitabine combined treatment trigger synergistic antitumor effects in pancreatic cancer through NF-κB mediated uPAR activation

BACKGROUND: Combined treatment of oncolytic adenoviruses with chemotherapeutic agents is foreseen as a therapeutic option for cancer. Here we have investigated the potential to use gemcitabine in combination with the oncolytic adenovirus AduPARE1A to treat pancreatic cancer and evaluate the underlyi...

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Detalles Bibliográficos
Autores principales: Maliandi, Maria Victoria, Mato-Berciano, Ana, Sobrevals, Luciano, Roué, Gaël, José, Anabel, Fillat, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521493/
https://www.ncbi.nlm.nih.gov/pubmed/26227809
http://dx.doi.org/10.1186/s12943-015-0413-2

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