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Ultrasound effects on brain-targeting mannosylated liposomes: in vitro and blood–brain barrier transport investigations
Delivering drugs to intracerebral regions can be accomplished by improving the capacity of transport through blood–brain barrier. Using sertraline as model drug for brain targeting, the current study aimed at modifying its liposomal vesicles with mannopyranoside. Box-Behnken design was employed to s...
Autores principales: | Zidan, Ahmed S, Aldawsari, Hibah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521675/ https://www.ncbi.nlm.nih.gov/pubmed/26244012 http://dx.doi.org/10.2147/DDDT.S87906 |
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