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Effects of exendin-4, a glucagon like peptide-1 receptor agonist, on neutrophil count and inflammatory cytokines in a rat model of endotoxemia
BACKGROUND: Sepsis remains a major cause of morbidity and mortality. A variety of strategies targeting modulation of the pro-inflammatory response associated with early sepsis have been reported without clinical success. GLP-1 enhances glucose-stimulated insulin secretion. In addition, it was shown...
Autores principales: | Yanay, Ofer, Bailey, Adam L, Kernan, Kelly, Zimmerman, Jerry J, Osborne, William R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521677/ https://www.ncbi.nlm.nih.gov/pubmed/26244029 http://dx.doi.org/10.2147/JIR.S84993 |
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