Withaferin A Induces Cell Death Selectively in Androgen-Independent Prostate Cancer Cells but Not in Normal Fibroblast Cells

Withaferin A (WA), a major bioactive component of the Indian herb Withania somnifera, induces cell death (apoptosis/necrosis) in multiple types of tumor cells, but the molecular mechanism underlying this cytotoxicity remains elusive. We report here that 2 μM WA induced cell death selectively in andr...

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Detalles Bibliográficos
Autores principales: Nishikawa, Yukihiro, Okuzaki, Daisuke, Fukushima, Kohshiro, Mukai, Satomi, Ohno, Shouichi, Ozaki, Yuki, Yabuta, Norikazu, Nojima, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521694/
https://www.ncbi.nlm.nih.gov/pubmed/26230090
http://dx.doi.org/10.1371/journal.pone.0134137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521694/
https://www.ncbi.nlm.nih.gov/pubmed/26230090
http://dx.doi.org/10.1371/journal.pone.0134137

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