Type 1 Diabetes Prone NOD Mice Have Diminished Cxcr1 mRNA Expression in Polymorphonuclear Neutrophils and CD4+ T Lymphocytes

In humans, CXCR1 and CXCR2 are two homologous proteins that bind ELR+ chemokines. Both receptors play fundamental roles in neutrophil functions such as migration and reactive oxygen species production. Mouse Cxcr1 and Cxcr2 genes are located in an insulin-dependent diabetes genetic susceptibility lo...

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Detalles Bibliográficos
Autores principales: Haurogné, Karine, Pavlovic, Marija, Rogniaux, Hélène, Bach, Jean-Marie, Lieubeau, Blandine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521788/
https://www.ncbi.nlm.nih.gov/pubmed/26230114
http://dx.doi.org/10.1371/journal.pone.0134365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521788/
https://www.ncbi.nlm.nih.gov/pubmed/26230114
http://dx.doi.org/10.1371/journal.pone.0134365

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