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Type 1 Diabetes Prone NOD Mice Have Diminished Cxcr1 mRNA Expression in Polymorphonuclear Neutrophils and CD4+ T Lymphocytes
In humans, CXCR1 and CXCR2 are two homologous proteins that bind ELR+ chemokines. Both receptors play fundamental roles in neutrophil functions such as migration and reactive oxygen species production. Mouse Cxcr1 and Cxcr2 genes are located in an insulin-dependent diabetes genetic susceptibility lo...
Autores principales: | Haurogné, Karine, Pavlovic, Marija, Rogniaux, Hélène, Bach, Jean-Marie, Lieubeau, Blandine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521788/ https://www.ncbi.nlm.nih.gov/pubmed/26230114 http://dx.doi.org/10.1371/journal.pone.0134365 |
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