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Ablation of CCAAT/Enhancer-Binding Protein Delta (C/EBPD): Increased Plaque Burden in a Murine Alzheimer’s Disease Model

Alzheimer’s disease (AD) and prion diseases carry a significant inflammatory component. The astrocytic overexpression of CCAAT/enhancer-binding protein delta (C/EBPD) in prion- and AD-affected brain tissue prompted us to study the role of this transcription factor in murine model systems of these di...

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Detalles Bibliográficos
Autores principales: Lutzenberger, Manuel, Burwinkel, Michael, Riemer, Constanze, Bode, Victoria, Baier, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521790/
https://www.ncbi.nlm.nih.gov/pubmed/26230261
http://dx.doi.org/10.1371/journal.pone.0134228