Cargando…

Bioinformatic Challenges in Clinical Diagnostic Application of Targeted Next Generation Sequencing: Experience from Pheochromocytoma

BACKGROUND: Recent studies have demonstrated equal quality of targeted next generation sequencing (NGS) compared to Sanger Sequencing. Whereas these novel sequencing processes have a validated robust performance, choice of enrichment method and different available bioinformatic software as reliable...

Descripción completa

Detalles Bibliográficos
Autores principales:	Crona, Joakim, Ljungström, Viktor, Welin, Staffan, Walz, Martin K., Hellman, Per, Björklund, Peyman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521794/ https://www.ncbi.nlm.nih.gov/pubmed/26230854 http://dx.doi.org/10.1371/journal.pone.0133210

Ejemplares similares

Next-generation sequencing in the clinical genetic screening of patients with pheochromocytoma and paraganglioma
por: Crona, Joakim, et al.
Publicado: (2013)

RNA-Sequencing Analysis of Adrenocortical Carcinoma, Pheochromocytoma and Paraganglioma from a Pan-Cancer Perspective
por: Crona, Joakim, et al.
Publicado: (2018)

Integrative Genetic Characterization and Phenotype Correlations in Pheochromocytoma and Paraganglioma Tumours
por: Crona, Joakim, et al.
Publicado: (2014)

Global DNA Methylation Analysis Identifies Two Discrete clusters of Pheochromocytoma with Distinct Genomic and Genetic Alterations
por: Backman, Samuel, et al.
Publicado: (2017)

Overall Survival in Patients with Stage IV Pan-NET Eligible for Liver Transplantation
por: Kjaer, Josefine, et al.
Publicado: (2022)

(11)C-hydroxy-ephedrine-PET/CT in the Diagnosis of Pheochromocytoma and Paraganglioma
por: Vyakaranam, Achyut Ram, et al.
Publicado: (2019)

Systemic Treatment of Gastroenteropancreatic Neuroendocrine Carcinoma
por: Mollazadegan, Kazhan, et al.
Publicado: (2021)

Favorable Outcome in Patients with Pheochromocytoma and Paraganglioma Treated with (177)Lu-DOTATATE
por: Vyakaranam, Achyut Ram, et al.
Publicado: (2019)

Bioinformatics for Next Generation Sequencing Data
por: Magi, Alberto, et al.
Publicado: (2010)

Translational Bioinformatics for Diagnostic and Prognostic Prediction of Prostate Cancer in the Next-Generation Sequencing Era
por: Chen, Jiajia, et al.
Publicado: (2013)

Poor outcome after systemic therapy in secondary high-grade pancreatic neuroendocrine tumors
por: Mollazadegan, Kazhan, et al.
Publicado: (2022)

Risk of complications after core needle biopsy in pheochromocytoma/paraganglioma
por: Zhang, Liang, et al.
Publicado: (2023)

Next-Generation Sequencing in Clinical Molecular Diagnostics of Cancer: Advantages and Challenges
por: Luthra, Rajyalakshmi, et al.
Publicado: (2015)

Next-generation Sequencing Bioinformatics: Guidance between the Sequencing and Sign out
por: Szymanski, Jeffrey, et al.
Publicado: (2018)

Germline Pathogenic Variants Identified by Targeted Next-Generation Sequencing of Susceptibility Genes in Pheochromocytoma and Paraganglioma
por: Yalcintepe, Sinem, et al.
Publicado: (2021)

Bioinformatics Methods and Biological Interpretation for Next-Generation Sequencing Data
por: Wang, Guohua, et al.
Publicado: (2015)

Next Generation Sequencing and Bioinformatics Analysis of Family Genetic Inheritance
por: Kanzi, Aquillah M., et al.
Publicado: (2020)

Scalable Newborn Screening Solutions: Bioinformatics and Next-Generation Sequencing
por: Ruiz-Schultz, Nicole, et al.
Publicado: (2021)

The next meta-challenge for Bioinformatics
por: Valdivia-Granda, Willy
Publicado: (2008)

Guidelines for diagnostic next-generation sequencing
por: Matthijs, Gert, et al.
Publicado: (2016)

Challenges in Molecular Diagnostics of Channelopathies in the Next-Generation Sequencing Era: Less Is More?
por: Novelli, Valeria, et al.
Publicado: (2016)

Metagenomic Next-Generation Sequencing for Diagnostically Challenging Mucormycosis in Patients with Hematological Malignancies
por: Zhang, Meng, et al.
Publicado: (2022)

Computational and Bioinformatics Frameworks for Next-Generation Whole Exome and Genome Sequencing
por: Dolled-Filhart, Marisa P., et al.
Publicado: (2013)

Microsatellites for Next-Generation Ecologists: A Post-Sequencing Bioinformatics Pipeline
por: Fernandez-Silva, Iria, et al.
Publicado: (2013)

Bioinformatics and Computational Tools for Next-Generation Sequencing Analysis in Clinical Genetics
por: Pereira, Rute, et al.
Publicado: (2020)

An Introduction to Next Generation Sequencing Bioinformatic Analysis in Gut Microbiome Studies
por: Gao, Bei, et al.
Publicado: (2021)

Benefit of Primary Tumor Resection in Stage IV, Grade 1 and 2, Pancreatic Neuroendocrine Tumors: A Propensity-Score Matched Cohort Study
por: Kjaer, Josefine, et al.
Publicado: (2022)

Five Percent Variant Allele Frequency Is a Reliable Reporting Threshold for TP53 Variants Detected by Next Generation Sequencing in Chronic Lymphocytic Leukemia in the Clinical Setting
por: Pandzic, Tatjana, et al.
Publicado: (2022)

RNA Sequencing Provides Novel Insights into the Transcriptome of Aldosterone Producing Adenomas
por: Backman, Samuel, et al.
Publicado: (2019)

A practical, bioinformatic workflow system for large data sets generated by next-generation sequencing
por: Cantacessi, Cinzia, et al.
Publicado: (2010)

Identification of novel genes in aging osteoblasts using next-generation sequencing and bioinformatics
por: Chen, Yi-Jen, et al.
Publicado: (2017)

Food Safety in the Age of Next Generation Sequencing, Bioinformatics, and Open Data Access
por: Taboada, Eduardo N., et al.
Publicado: (2017)

Long-term outcome after resection and thermal hepatic ablation of pancreatic neuroendocrine tumour liver metastases
por: Kjaer, J, et al.
Publicado: (2021)

Challenges in the introduction of next-generation sequencing (NGS) for diagnostics of myeloid malignancies into clinical routine use
por: Bacher, Ulrike, et al.
Publicado: (2018)

Applications of Next-Generation Sequencing Technologies to Diagnostic Virology
por: Barzon, Luisa, et al.
Publicado: (2011)

Diagnostics of Primary Immunodeficiencies through Next-Generation Sequencing
por: Gallo, Vera, et al.
Publicado: (2016)

Next-generation sequencing diagnostics of bacteremia in septic patients
por: Grumaz, Silke, et al.
Publicado: (2016)

Next-generation sequencing diagnostics of bacteremia in pediatric sepsis
por: Schmoch, Thomas, et al.
Publicado: (2021)

The diagnostic value of next-generation sequencing technology in sepsis
por: Cao, Xiao-guang, et al.
Publicado: (2022)

A Rare Coexistence of Pheochromocytoma and Parkinson's Disease With Diagnostic Challenges
por: Matsumura-Matsuda, Erika, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_3dod2ujf1drdtbfafouijkmkn8