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HCV NS5A Up-Regulates COX-2 Expression via IL-8-Mediated Activation of the ERK/JNK MAPK Pathway
Chronic hepatitis C virus (HCV) infection leads to intrahepatic inflammation and liver cell injury, which are considered a risk factor for virus-associated hepatitis, cirrhosis, and hepatocellular carcinoma worldwide. Inflammatory cytokines are critical components of the immune system and influence...
Autores principales: | Chen, Wei-Chun, Tseng, Chin-Kai, Chen, Yen-Hsu, Lin, Chun-Kuang, Hsu, Shih-hsien, Wang, Shen-Nien, Lee, Jin-Ching |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521820/ https://www.ncbi.nlm.nih.gov/pubmed/26231035 http://dx.doi.org/10.1371/journal.pone.0133264 |
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