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Direct Facilitatory Role of Paragigantocellularis Neurons in Opiate Withdrawal-Induced Hyperactivity of Rat Locus Coeruleus Neurons: An In Vitro Study

Studies have shown that following opiate withdrawal, the spontaneous discharge rate of locus coeruleus (LC) neurons remarkably increases. Combination of intrinsic mechanisms with extrinsic excitatory modulations mediates the withdrawal-induced hyperactivity of LC neurons. The nucleus paragigantocell...

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Detalles Bibliográficos
Autores principales: Kaeidi, Ayat, Azizi, Hossein, Javan, Mohammad, Ahmadi Soleimani, S. Mohammad, Fathollahi, Yaghoub, Semnanian, Saeed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521852/
https://www.ncbi.nlm.nih.gov/pubmed/26230639
http://dx.doi.org/10.1371/journal.pone.0134873

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