Cargando…
Antibacterial and Antifungal Activity of ZnO Containing Glasses
A new family of non-toxic biocides based on low melting point (1250°C) transparent glasses with high content of ZnO (15–40wt%) belonging to the miscibility region of the B(2)O(3)-SiO(2)-Na(2)O-ZnO system has been developed. These glasses have shown an excellent biocide activity (logarithmic reductio...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521915/ https://www.ncbi.nlm.nih.gov/pubmed/26230940 http://dx.doi.org/10.1371/journal.pone.0132709 |
_version_ | 1782383882908205056 |
---|---|
author | Esteban-Tejeda, Leticia Prado, Catuxa Cabal, Belén Sanz, Jesús Torrecillas, Ramón Moya, José Serafín |
author_facet | Esteban-Tejeda, Leticia Prado, Catuxa Cabal, Belén Sanz, Jesús Torrecillas, Ramón Moya, José Serafín |
author_sort | Esteban-Tejeda, Leticia |
collection | PubMed |
description | A new family of non-toxic biocides based on low melting point (1250°C) transparent glasses with high content of ZnO (15–40wt%) belonging to the miscibility region of the B(2)O(3)-SiO(2)-Na(2)O-ZnO system has been developed. These glasses have shown an excellent biocide activity (logarithmic reduction >3) against Gram- (E. coli), Gram+ (S. aureus) and yeast (C. krusei); they are chemically stable in different media (distilled water, sea-like water, LB and DMEN media) as well as biocompatible. The cytotoxicity was evaluated by the Neutral Red Uptake using NIH-3T3 (mouse embryonic fibroblast cells) and the cell viability was >80%. These new glasses can be considered in several and important applications in the field of inorganic non-toxic biocide agents such as medical implants, surgical equipment, protective apparels in hospitals, water purifications systems, food packaging, food storages or textiles. |
format | Online Article Text |
id | pubmed-4521915 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-45219152015-08-06 Antibacterial and Antifungal Activity of ZnO Containing Glasses Esteban-Tejeda, Leticia Prado, Catuxa Cabal, Belén Sanz, Jesús Torrecillas, Ramón Moya, José Serafín PLoS One Research Article A new family of non-toxic biocides based on low melting point (1250°C) transparent glasses with high content of ZnO (15–40wt%) belonging to the miscibility region of the B(2)O(3)-SiO(2)-Na(2)O-ZnO system has been developed. These glasses have shown an excellent biocide activity (logarithmic reduction >3) against Gram- (E. coli), Gram+ (S. aureus) and yeast (C. krusei); they are chemically stable in different media (distilled water, sea-like water, LB and DMEN media) as well as biocompatible. The cytotoxicity was evaluated by the Neutral Red Uptake using NIH-3T3 (mouse embryonic fibroblast cells) and the cell viability was >80%. These new glasses can be considered in several and important applications in the field of inorganic non-toxic biocide agents such as medical implants, surgical equipment, protective apparels in hospitals, water purifications systems, food packaging, food storages or textiles. Public Library of Science 2015-07-31 /pmc/articles/PMC4521915/ /pubmed/26230940 http://dx.doi.org/10.1371/journal.pone.0132709 Text en © 2015 Esteban-Tejeda et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Esteban-Tejeda, Leticia Prado, Catuxa Cabal, Belén Sanz, Jesús Torrecillas, Ramón Moya, José Serafín Antibacterial and Antifungal Activity of ZnO Containing Glasses |
title | Antibacterial and Antifungal Activity of ZnO Containing Glasses |
title_full | Antibacterial and Antifungal Activity of ZnO Containing Glasses |
title_fullStr | Antibacterial and Antifungal Activity of ZnO Containing Glasses |
title_full_unstemmed | Antibacterial and Antifungal Activity of ZnO Containing Glasses |
title_short | Antibacterial and Antifungal Activity of ZnO Containing Glasses |
title_sort | antibacterial and antifungal activity of zno containing glasses |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521915/ https://www.ncbi.nlm.nih.gov/pubmed/26230940 http://dx.doi.org/10.1371/journal.pone.0132709 |
work_keys_str_mv | AT estebantejedaleticia antibacterialandantifungalactivityofznocontainingglasses AT pradocatuxa antibacterialandantifungalactivityofznocontainingglasses AT cabalbelen antibacterialandantifungalactivityofznocontainingglasses AT sanzjesus antibacterialandantifungalactivityofznocontainingglasses AT torrecillasramon antibacterialandantifungalactivityofznocontainingglasses AT moyajoseserafin antibacterialandantifungalactivityofznocontainingglasses |