c-Myc and AMPK Control Cellular Energy Levels by Cooperatively Regulating Mitochondrial Structure and Function

The c-Myc (Myc) oncoprotein and AMP-activated protein kinase (AMPK) regulate glycolysis and oxidative phosphorylation (Oxphos) although often for different purposes. Because Myc over-expression depletes ATP with the resultant activation of AMPK, we explored the potential co-dependency of and cross-t...

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Detalles Bibliográficos
Autores principales: Edmunds, Lia R., Sharma, Lokendra, Wang, Huabo, Kang, Audry, d’Souza, Sonia, Lu, Jie, McLaughlin, Michael, Dolezal, James M., Gao, Xiaoli, Weintraub, Susan T., Ding, Ying, Zeng, Xuemei, Yates, Nathan, Prochownik, Edward V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521957/
https://www.ncbi.nlm.nih.gov/pubmed/26230505
http://dx.doi.org/10.1371/journal.pone.0134049

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