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Structural and functional influences of coagulation factor XIII subunit B heterozygous missense mutants

The coagulation factor XIII(FXIII) is a plasma circulating heterotetrameric protransglutaminase that acts at the end of the coagulation cascade by covalently cross-linking preformed fibrin clots (to themselves and to fibrinolytic inhibitors) in order to stabilize them against fibrinolysis. It circul...

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Detalles Bibliográficos
Autores principales: Thomas, Anne, Biswas, Arijit, Ivaskevicius, Vytautas, Oldenburg, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521963/
https://www.ncbi.nlm.nih.gov/pubmed/26247044
http://dx.doi.org/10.1002/mgg3.138