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SDF-1alpha concentration dependent modulation of RhoA and Rac1 modifies breast cancer and stromal cells interaction

BACKGROUND: The interaction of SDF-1alpha with its receptor CXCR4 plays a role in the occurrence of distant metastasis in many solid tumors. This interaction increases migration from primary sites as well as homing at distant sites. METHODS: Here we investigated how SDF-1α could modulate both migrat...

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Detalles Bibliográficos
Autores principales:	Pasquier, Jennifer, Abu-Kaoud, Nadine, Abdesselem, Houari, Madani, Aisha, Hoarau-Véchot, Jessica, Thawadi, Hamda Al., Vidal, Fabien, Couderc, Bettina, Favre, Gilles, Rafii, Arash
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522077/ https://www.ncbi.nlm.nih.gov/pubmed/26231656 http://dx.doi.org/10.1186/s12885-015-1556-7

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