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The BisPCR(2) method for targeted bisulfite sequencing

BACKGROUND: DNA methylation has emerged as an important regulator of development and disease, necessitating the design of more efficient and cost-effective methods for detecting and quantifying this epigenetic modification. Next-generation sequencing (NGS) techniques offer single base resolution of...

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Detalles Bibliográficos
Autores principales: Bernstein, Diana L, Kameswaran, Vasumathi, Le Lay, John E, Sheaffer, Karyn L, Kaestner, Klaus H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522100/
https://www.ncbi.nlm.nih.gov/pubmed/26236400
http://dx.doi.org/10.1186/s13072-015-0020-x