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A review of 3D first-pass, whole-heart, myocardial perfusion cardiovascular magnetic resonance

A comprehensive review is undertaken of the methods available for 3D whole-heart first-pass perfusion (FPP) and their application to date, with particular focus on possible acceleration techniques. Following a summary of the parameters typically desired of 3D FPP methods, the review explains the mec...

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Autores principales: Fair, Merlin J., Gatehouse, Peter D., DiBella, Edward V. R., Firmin, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522116/
https://www.ncbi.nlm.nih.gov/pubmed/26231784
http://dx.doi.org/10.1186/s12968-015-0162-9
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author Fair, Merlin J.
Gatehouse, Peter D.
DiBella, Edward V. R.
Firmin, David N.
author_facet Fair, Merlin J.
Gatehouse, Peter D.
DiBella, Edward V. R.
Firmin, David N.
author_sort Fair, Merlin J.
collection PubMed
description A comprehensive review is undertaken of the methods available for 3D whole-heart first-pass perfusion (FPP) and their application to date, with particular focus on possible acceleration techniques. Following a summary of the parameters typically desired of 3D FPP methods, the review explains the mechanisms of key acceleration techniques and their potential use in FPP for attaining 3D acquisitions. The mechanisms include rapid sequences, non-Cartesian k-space trajectories, reduced k-space acquisitions, parallel imaging reconstructions and compressed sensing. An attempt is made to explain, rather than simply state, the varying methods with the hope that it will give an appreciation of the different components making up a 3D FPP protocol. Basic estimates demonstrating the required total acceleration factors in typical 3D FPP cases are included, providing context for the extent that each acceleration method can contribute to the required imaging speed, as well as potential limitations in present 3D FPP literature. Although many 3D FPP methods are too early in development for the type of clinical trials required to show any clear benefit over current 2D FPP methods, the review includes the small but growing quantity of clinical research work already using 3D FPP, alongside the more technical work. Broader challenges concerning FPP such as quantitative analysis are not covered, but challenges with particular impact on 3D FPP methods, particularly with regards to motion effects, are discussed along with anticipated future work in the field.
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spelling pubmed-45221162015-09-10 A review of 3D first-pass, whole-heart, myocardial perfusion cardiovascular magnetic resonance Fair, Merlin J. Gatehouse, Peter D. DiBella, Edward V. R. Firmin, David N. J Cardiovasc Magn Reson Review A comprehensive review is undertaken of the methods available for 3D whole-heart first-pass perfusion (FPP) and their application to date, with particular focus on possible acceleration techniques. Following a summary of the parameters typically desired of 3D FPP methods, the review explains the mechanisms of key acceleration techniques and their potential use in FPP for attaining 3D acquisitions. The mechanisms include rapid sequences, non-Cartesian k-space trajectories, reduced k-space acquisitions, parallel imaging reconstructions and compressed sensing. An attempt is made to explain, rather than simply state, the varying methods with the hope that it will give an appreciation of the different components making up a 3D FPP protocol. Basic estimates demonstrating the required total acceleration factors in typical 3D FPP cases are included, providing context for the extent that each acceleration method can contribute to the required imaging speed, as well as potential limitations in present 3D FPP literature. Although many 3D FPP methods are too early in development for the type of clinical trials required to show any clear benefit over current 2D FPP methods, the review includes the small but growing quantity of clinical research work already using 3D FPP, alongside the more technical work. Broader challenges concerning FPP such as quantitative analysis are not covered, but challenges with particular impact on 3D FPP methods, particularly with regards to motion effects, are discussed along with anticipated future work in the field. BioMed Central 2015-08-01 /pmc/articles/PMC4522116/ /pubmed/26231784 http://dx.doi.org/10.1186/s12968-015-0162-9 Text en © Fair et al. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Fair, Merlin J.
Gatehouse, Peter D.
DiBella, Edward V. R.
Firmin, David N.
A review of 3D first-pass, whole-heart, myocardial perfusion cardiovascular magnetic resonance
title A review of 3D first-pass, whole-heart, myocardial perfusion cardiovascular magnetic resonance
title_full A review of 3D first-pass, whole-heart, myocardial perfusion cardiovascular magnetic resonance
title_fullStr A review of 3D first-pass, whole-heart, myocardial perfusion cardiovascular magnetic resonance
title_full_unstemmed A review of 3D first-pass, whole-heart, myocardial perfusion cardiovascular magnetic resonance
title_short A review of 3D first-pass, whole-heart, myocardial perfusion cardiovascular magnetic resonance
title_sort review of 3d first-pass, whole-heart, myocardial perfusion cardiovascular magnetic resonance
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522116/
https://www.ncbi.nlm.nih.gov/pubmed/26231784
http://dx.doi.org/10.1186/s12968-015-0162-9
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