Cargando…
The cytohesin guanosine exchange factors (GEFs) are required to promote HGF-mediated renal recovery after acute kidney injury (AKI) in mice
The lack of current treatment and preventable measures for acute kidney injury (AKI) in hospitalized patients results in an increased mortality rate of up to 80% and elevated health costs. Additionally, if not properly repaired, those who survive AKI may develop fibrosis and long-term kidney damage....
Autores principales: | Reviriego-Mendoza, Marta M, Santy, Lorraine C |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522160/ https://www.ncbi.nlm.nih.gov/pubmed/26116550 http://dx.doi.org/10.14814/phy2.12442 |
Ejemplares similares
-
ARF-GEF cytohesin-2/ARNO regulates R-Ras and α5-integrin recycling through an EHD1-positive compartment
por: Salem, Joseph C., et al.
Publicado: (2015) -
The Cytohesin Coiled-Coil Domain Interacts with Threonine 276 to Control Membrane Association
por: Hiester, Kevin G., et al.
Publicado: (2013) -
The scaffolding protein GRASP/Tamalin directly binds to Dock180 as well as to cytohesins facilitating GTPase crosstalk in epithelial cell migration
por: Attar, Myriam A, et al.
Publicado: (2013) -
GRASP and IPCEF Promote ARF-to-Rac Signaling and Cell Migration by Coordinating the Association of ARNO/cytohesin 2 with Dock180
por: White, David T., et al.
Publicado: (2010) -
The GEF Cytohesin-2/ARNO Mediates Resistin induced Phenotypic Switching in Vascular Smooth Muscle Cells
por: Heun, Yvonn, et al.
Publicado: (2020)