Variable phenotypic expressivity in inbred retinal degeneration mouse lines: A comparative study of C3H/HeOu and FVB/N rd1 mice

PURPOSE: Recent advances in optogenetics and gene therapy have led to promising new treatment strategies for blindness caused by retinal photoreceptor loss. Preclinical studies often rely on the retinal degeneration 1 (rd1 or Pde6b(rd1)) retinitis pigmentosa (RP) mouse model. The rd1 founder mutatio...

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Detalles Bibliográficos
Autores principales: van Wyk, Michiel, Schneider, Sabine, Kleinlogel, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522243/
https://www.ncbi.nlm.nih.gov/pubmed/26283863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522243/
https://www.ncbi.nlm.nih.gov/pubmed/26283863

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