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Generation of a Homozygous Transgenic Rat Strain Stably Expressing a Calcium Sensor Protein for Direct Examination of Calcium Signaling

In drug discovery, prediction of selectivity and toxicity require the evaluation of cellular calcium homeostasis. The rat is a preferred laboratory animal for pharmacology and toxicology studies, while currently no calcium indicator protein expressing rat model is available. We established a transge...

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Detalles Bibliográficos
Autores principales:	Szebényi, Kornélia, Füredi, András, Kolacsek, Orsolya, Pergel, Enikő, Bősze, Zsuzsanna, Bender, Balázs, Vajdovich, Péter, Tóvári, József, Homolya, László, Szakács, Gergely, Héja, László, Enyedi, Ágnes, Sarkadi, Balázs, Apáti, Ágota, Orbán, Tamás I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522653/ https://www.ncbi.nlm.nih.gov/pubmed/26234466 http://dx.doi.org/10.1038/srep12645

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