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Pathogenicity of Bovine Neonatal Pancytopenia-associated vaccine-induced alloantibodies correlates with Major Histocompatibility Complex class I expression

Bovine Neonatal Pancytopenia (BNP), a fatal bleeding syndrome of neonatal calves, is caused by maternal alloantibodies absorbed from colostrum and is characterized by lymphocytopenia, thrombocytopenia and bone marrow hypoplasia. An inactivated viral vaccine is the likely source of alloantigens induc...

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Detalles Bibliográficos
Autores principales: Benedictus, Lindert, Luteijn, Rutger D., Otten, Henny, Jan Lebbink, Robert, van Kooten, Peter J. S., Wiertz, Emmanuel J. H. J., Rutten, Victor P. M. G., Koets, Ad P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522679/
https://www.ncbi.nlm.nih.gov/pubmed/26235972
http://dx.doi.org/10.1038/srep12748