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Case report of renal cell carcinoma in automobile manufacturing factory worker due to trichloroethylene exposure in Korea
BACKGROUND: The aim of this paper was report first case of renal cell carcinoma developed in a worker who worked in an automobile manufacture line which handles trichloroethylene in Korea. CASE PRESENTATION: To clarify the relationship between the onset of renal cell carcinoma in 52-years old male w...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522957/ https://www.ncbi.nlm.nih.gov/pubmed/26240754 http://dx.doi.org/10.1186/s40557-015-0068-x |
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author | Lee, June-Hee Kim, Inah Seok, Hongdeok Park, Inhyo Hwang, Jungho Park, Jae-Oh Won, Jong-Uk Roh, Jaehoon |
author_facet | Lee, June-Hee Kim, Inah Seok, Hongdeok Park, Inhyo Hwang, Jungho Park, Jae-Oh Won, Jong-Uk Roh, Jaehoon |
author_sort | Lee, June-Hee |
collection | PubMed |
description | BACKGROUND: The aim of this paper was report first case of renal cell carcinoma developed in a worker who worked in an automobile manufacture line which handles trichloroethylene in Korea. CASE PRESENTATION: To clarify the relationship between the onset of renal cell carcinoma in 52-years old male worker and the exposure to trichloroethylene, document studies and work environment measurement were done. Past work environment exposure data were reviewed and medical history and surgery records of the worker were also reviewed. The patient had no personal risk factor related to renal cell carcinoma except for his smoking habit of quarter a pack per day for twenty years, and since trichloroethylene was not part of measurement criteria, past work environment risk assessment data could not verify the exposure. The exposure level is deduced by analyzing material exposure level of work environments which has similar processes in data from revised research of chemical exposure standard and work environment validity assessment. Evaluation Committee of Epidemiologic Survey decided that there are relevant relationship between the exposure and the disease, though we do not have exact data during that period, most experts agree that in every factories they used trichloroethylene without any direction. CONCLUSIONS: From the relevant medical history and the results of the usage of trichloroethylene in the relevant industries, and initial discovery of renal cell carcinoma at health inspection sonogram in 2001, it can be concluded that suggests significant causal relationship between the exposure to trichloroethylene and renal cell carcinoma onset, thus reporting it to be the first domestic case declared to be occupational disease. |
format | Online Article Text |
id | pubmed-4522957 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-45229572015-08-04 Case report of renal cell carcinoma in automobile manufacturing factory worker due to trichloroethylene exposure in Korea Lee, June-Hee Kim, Inah Seok, Hongdeok Park, Inhyo Hwang, Jungho Park, Jae-Oh Won, Jong-Uk Roh, Jaehoon Ann Occup Environ Med Case Report BACKGROUND: The aim of this paper was report first case of renal cell carcinoma developed in a worker who worked in an automobile manufacture line which handles trichloroethylene in Korea. CASE PRESENTATION: To clarify the relationship between the onset of renal cell carcinoma in 52-years old male worker and the exposure to trichloroethylene, document studies and work environment measurement were done. Past work environment exposure data were reviewed and medical history and surgery records of the worker were also reviewed. The patient had no personal risk factor related to renal cell carcinoma except for his smoking habit of quarter a pack per day for twenty years, and since trichloroethylene was not part of measurement criteria, past work environment risk assessment data could not verify the exposure. The exposure level is deduced by analyzing material exposure level of work environments which has similar processes in data from revised research of chemical exposure standard and work environment validity assessment. Evaluation Committee of Epidemiologic Survey decided that there are relevant relationship between the exposure and the disease, though we do not have exact data during that period, most experts agree that in every factories they used trichloroethylene without any direction. CONCLUSIONS: From the relevant medical history and the results of the usage of trichloroethylene in the relevant industries, and initial discovery of renal cell carcinoma at health inspection sonogram in 2001, it can be concluded that suggests significant causal relationship between the exposure to trichloroethylene and renal cell carcinoma onset, thus reporting it to be the first domestic case declared to be occupational disease. BioMed Central 2015-08-03 /pmc/articles/PMC4522957/ /pubmed/26240754 http://dx.doi.org/10.1186/s40557-015-0068-x Text en © Lee et al. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Case Report Lee, June-Hee Kim, Inah Seok, Hongdeok Park, Inhyo Hwang, Jungho Park, Jae-Oh Won, Jong-Uk Roh, Jaehoon Case report of renal cell carcinoma in automobile manufacturing factory worker due to trichloroethylene exposure in Korea |
title | Case report of renal cell carcinoma in automobile manufacturing factory worker due to trichloroethylene exposure in Korea |
title_full | Case report of renal cell carcinoma in automobile manufacturing factory worker due to trichloroethylene exposure in Korea |
title_fullStr | Case report of renal cell carcinoma in automobile manufacturing factory worker due to trichloroethylene exposure in Korea |
title_full_unstemmed | Case report of renal cell carcinoma in automobile manufacturing factory worker due to trichloroethylene exposure in Korea |
title_short | Case report of renal cell carcinoma in automobile manufacturing factory worker due to trichloroethylene exposure in Korea |
title_sort | case report of renal cell carcinoma in automobile manufacturing factory worker due to trichloroethylene exposure in korea |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522957/ https://www.ncbi.nlm.nih.gov/pubmed/26240754 http://dx.doi.org/10.1186/s40557-015-0068-x |
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