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MiR-106b induces cell radioresistance via the PTEN/PI3K/AKT pathways and p21 in colorectal cancer
BACKGROUND: Radioresistance is a challenge in the treatment of patients with colorectal cancer (CRC). Individuals display different therapeutic responses to preoperative radiotherapy, and the need of targeted therapies is urgent. MicroRNAs (miRNAs) are involved in essential biological activities, in...
Autores principales: | Zheng, Lin, Zhang, Yuqin, Liu, Yan, Zhou, Min, Lu, Yanxia, Yuan, Li, Zhang, Chao, Hong, Min, Wang, Shuang, Li, Xuenong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522974/ https://www.ncbi.nlm.nih.gov/pubmed/26238857 http://dx.doi.org/10.1186/s12967-015-0592-z |
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