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MiR-106b induces cell radioresistance via the PTEN/PI3K/AKT pathways and p21 in colorectal cancer

BACKGROUND: Radioresistance is a challenge in the treatment of patients with colorectal cancer (CRC). Individuals display different therapeutic responses to preoperative radiotherapy, and the need of targeted therapies is urgent. MicroRNAs (miRNAs) are involved in essential biological activities, in...

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Detalles Bibliográficos
Autores principales: Zheng, Lin, Zhang, Yuqin, Liu, Yan, Zhou, Min, Lu, Yanxia, Yuan, Li, Zhang, Chao, Hong, Min, Wang, Shuang, Li, Xuenong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522974/
https://www.ncbi.nlm.nih.gov/pubmed/26238857
http://dx.doi.org/10.1186/s12967-015-0592-z

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