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Quantification of epigenetic biomarkers: an evaluation of established and emerging methods for DNA methylation analysis

BACKGROUND: DNA methylation is an important epigenetic mechanism in several human diseases, most notably cancer. The quantitative analysis of DNA methylation patterns has the potential to serve as diagnostic and prognostic biomarkers, however, there is currently a lack of consensus regarding the opt...

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Detalles Bibliográficos
Autores principales: Redshaw, Nicholas, Huggett, Jim F, Taylor, Martin S, Foy, Carole A, Devonshire, Alison S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523014/
https://www.ncbi.nlm.nih.gov/pubmed/25539843
http://dx.doi.org/10.1186/1471-2164-15-1174