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A lifelong exposure to a Western-style diet, but not aging, alters global DNA methylation in mouse colon

BACKGROUND/OBJECTIVES: Previous studies have indicated that when compared to young mice, old mice have lower global DNA methylation and higher p16 promoter methylation in colonic mucosa, which is a common finding in colon cancer. It is also known that a Western-style diet (WSD) high in fat and calor...

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Detalles Bibliográficos
Autores principales:	Choi, Sang-Woon, Tammen, Stephanie A, Liu, Zhenhua, Friso, Simonetta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Nutrition Society and the Korean Society of Community Nutrition 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523478/ https://www.ncbi.nlm.nih.gov/pubmed/26244073 http://dx.doi.org/10.4162/nrp.2015.9.4.358

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