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TPX2 phosphorylation maintains metaphase spindle length by regulating microtubule flux

A steady-state metaphase spindle maintains constant length, although the microtubules undergo intensive dynamics. Tubulin dimers are incorporated at plus ends of spindle microtubules while they are removed from the minus ends, resulting in poleward movement. Such microtubule flux is regulated by the...

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Detalles Bibliográficos
Autores principales:	Fu, Jingyan, Bian, Minglei, Xin, Guangwei, Deng, Zhaoxuan, Luo, Jia, Guo, Xiao, Chen, Hao, Wang, Yao, Jiang, Qing, Zhang, Chuanmao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523612/ https://www.ncbi.nlm.nih.gov/pubmed/26240182 http://dx.doi.org/10.1083/jcb.201412109

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