A developmental biologist’s “outside-the-cell” thinking

A major gap in our understanding of cell biology is how cells generate and interact with their surrounding extracellular matrix. Studying this problem during development has been particularly fruitful. Recent work on the basement membrane in developmental systems is transforming our view of this mat...

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Detalles Bibliográficos
Autor principal: Sherwood, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
News
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523616/
https://www.ncbi.nlm.nih.gov/pubmed/26240181
http://dx.doi.org/10.1083/jcb.201501083
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author Sherwood, David R.
author_facet Sherwood, David R.
author_sort Sherwood, David R.
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description A major gap in our understanding of cell biology is how cells generate and interact with their surrounding extracellular matrix. Studying this problem during development has been particularly fruitful. Recent work on the basement membrane in developmental systems is transforming our view of this matrix from one of a static support structure to that of a dynamic scaffold that is regularly remodeled to actively shape tissues and direct cell behaviors.
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spelling pubmed-45236162016-02-03 A developmental biologist’s “outside-the-cell” thinking Sherwood, David R. J Cell Biol News A major gap in our understanding of cell biology is how cells generate and interact with their surrounding extracellular matrix. Studying this problem during development has been particularly fruitful. Recent work on the basement membrane in developmental systems is transforming our view of this matrix from one of a static support structure to that of a dynamic scaffold that is regularly remodeled to actively shape tissues and direct cell behaviors. The Rockefeller University Press 2015-08-03 /pmc/articles/PMC4523616/ /pubmed/26240181 http://dx.doi.org/10.1083/jcb.201501083 Text en © 2015 Sherwood This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle News
Sherwood, David R.
A developmental biologist’s “outside-the-cell” thinking
title A developmental biologist’s “outside-the-cell” thinking
title_full A developmental biologist’s “outside-the-cell” thinking
title_fullStr A developmental biologist’s “outside-the-cell” thinking
title_full_unstemmed A developmental biologist’s “outside-the-cell” thinking
title_short A developmental biologist’s “outside-the-cell” thinking
title_sort developmental biologist’s “outside-the-cell” thinking
topic News
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523616/
https://www.ncbi.nlm.nih.gov/pubmed/26240181
http://dx.doi.org/10.1083/jcb.201501083
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