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Real-time imaging of bHLH transcription factors reveals their dynamic control in the multipotency and fate choice of neural stem cells

The basic-helix-loop-helix (bHLH) transcription factors Ascl1/Mash1, Hes1, and Olig2 regulate the fate choice of neurons, astrocytes, and oligodendrocytes, respectively; however, these factors are coexpressed in self-renewing multipotent neural stem cells (NSCs) even before cell fate determination....

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Detalles Bibliográficos
Autores principales:	Imayoshi, Itaru, Ishidate, Fumiyoshi, Kageyama, Ryoichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523821/ https://www.ncbi.nlm.nih.gov/pubmed/26300726 http://dx.doi.org/10.3389/fncel.2015.00288

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