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Sensitivity of mRNA Translation

Using the dynamic mean-field approximation of the totally asymmetric simple exclusion process (TASEP), we investigate the effect of small changes in the initiation, elongation, and termination rates along the mRNA strand on the steady-state protein translation rate. We show that the sensitivity of m...

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Detalles Bibliográficos
Autores principales: Poker, Gilad, Margaliot, Michael, Tuller, Tamir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523843/
https://www.ncbi.nlm.nih.gov/pubmed/26238363
http://dx.doi.org/10.1038/srep12795