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Cancer care coordinators in stage III colon cancer: a cost-utility analysis

BACKGROUND: There is momentum internationally to improve coordination of complex care pathways. Robust evaluations of such interventions are scarce. This paper evaluates the cost-utility of cancer care coordinators for stage III colon cancer patients, who generally require surgery followed by chemot...

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Autores principales: Blakely, Tony, Collinson, Lucie, Kvizhinadze, Giorgi, Nair, Nisha, Foster, Rachel, Dennett, Elizabeth, Sarfati, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523949/
https://www.ncbi.nlm.nih.gov/pubmed/26238996
http://dx.doi.org/10.1186/s12913-015-0970-5
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author Blakely, Tony
Collinson, Lucie
Kvizhinadze, Giorgi
Nair, Nisha
Foster, Rachel
Dennett, Elizabeth
Sarfati, Diana
author_facet Blakely, Tony
Collinson, Lucie
Kvizhinadze, Giorgi
Nair, Nisha
Foster, Rachel
Dennett, Elizabeth
Sarfati, Diana
author_sort Blakely, Tony
collection PubMed
description BACKGROUND: There is momentum internationally to improve coordination of complex care pathways. Robust evaluations of such interventions are scarce. This paper evaluates the cost-utility of cancer care coordinators for stage III colon cancer patients, who generally require surgery followed by chemotherapy. METHODS: We compared a hospital-based nurse cancer care coordinator (CCC) with ‘business-as-usual’ (no dedicated coordination service) in stage III colon cancer patients in New Zealand. A discrete event microsimulation model was constructed to estimate quality-adjusted life-years (QALYs) and costs from a health system perspective. We used New Zealand data on colon cancer incidence, survival, and mortality as baseline input parameters for the model. We specified intervention input parameters using available literature and expert estimates. For example, that a CCC would improve the coverage of chemotherapy by 33 % (ranging from 9 to 65 %), reduce the time to surgery by 20 % (3 to 48 %), reduce the time to chemotherapy by 20 % (3 to 48 %), and reduce patient anxiety (reduction in disability weight of 33 %, ranging from 0 to 55 %). RESULTS: Much of the direct cost of a nurse CCC was balanced by savings in business-as-usual care coordination. Much of the health gain was through increased coverage of chemotherapy with a CCC (especially older patients), and reduced time to chemotherapy. Compared to ‘business-as-usual’, the cost per QALY of the CCC programme was $NZ 18,900 (≈ $US 15,600; 95 % UI: $NZ 13,400 to 24,600). By age, the CCC intervention was more cost-effective for colon cancer patients < 65 years ($NZ 9,400 per QALY). By ethnicity, the health gains were larger for Māori, but so too were the costs, meaning the cost-effectiveness was roughly comparable between ethnic groups. CONCLUSIONS: Such a nurse-led CCC intervention in New Zealand has acceptable cost-effectiveness for stage III colon cancer, meaning it probably merits funding. Each CCC programme will differ in its likely health gains and costs, making generalisation from this evaluation to other CCC interventions difficult. However, this evaluation suggests that CCC interventions that increase coverage of, and reduce time to, effective treatments may be cost-effective. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12913-015-0970-5) contains supplementary material, which is available to authorized users.
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spelling pubmed-45239492015-08-05 Cancer care coordinators in stage III colon cancer: a cost-utility analysis Blakely, Tony Collinson, Lucie Kvizhinadze, Giorgi Nair, Nisha Foster, Rachel Dennett, Elizabeth Sarfati, Diana BMC Health Serv Res Research Article BACKGROUND: There is momentum internationally to improve coordination of complex care pathways. Robust evaluations of such interventions are scarce. This paper evaluates the cost-utility of cancer care coordinators for stage III colon cancer patients, who generally require surgery followed by chemotherapy. METHODS: We compared a hospital-based nurse cancer care coordinator (CCC) with ‘business-as-usual’ (no dedicated coordination service) in stage III colon cancer patients in New Zealand. A discrete event microsimulation model was constructed to estimate quality-adjusted life-years (QALYs) and costs from a health system perspective. We used New Zealand data on colon cancer incidence, survival, and mortality as baseline input parameters for the model. We specified intervention input parameters using available literature and expert estimates. For example, that a CCC would improve the coverage of chemotherapy by 33 % (ranging from 9 to 65 %), reduce the time to surgery by 20 % (3 to 48 %), reduce the time to chemotherapy by 20 % (3 to 48 %), and reduce patient anxiety (reduction in disability weight of 33 %, ranging from 0 to 55 %). RESULTS: Much of the direct cost of a nurse CCC was balanced by savings in business-as-usual care coordination. Much of the health gain was through increased coverage of chemotherapy with a CCC (especially older patients), and reduced time to chemotherapy. Compared to ‘business-as-usual’, the cost per QALY of the CCC programme was $NZ 18,900 (≈ $US 15,600; 95 % UI: $NZ 13,400 to 24,600). By age, the CCC intervention was more cost-effective for colon cancer patients < 65 years ($NZ 9,400 per QALY). By ethnicity, the health gains were larger for Māori, but so too were the costs, meaning the cost-effectiveness was roughly comparable between ethnic groups. CONCLUSIONS: Such a nurse-led CCC intervention in New Zealand has acceptable cost-effectiveness for stage III colon cancer, meaning it probably merits funding. Each CCC programme will differ in its likely health gains and costs, making generalisation from this evaluation to other CCC interventions difficult. However, this evaluation suggests that CCC interventions that increase coverage of, and reduce time to, effective treatments may be cost-effective. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12913-015-0970-5) contains supplementary material, which is available to authorized users. BioMed Central 2015-08-05 /pmc/articles/PMC4523949/ /pubmed/26238996 http://dx.doi.org/10.1186/s12913-015-0970-5 Text en © Blakely et al. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Blakely, Tony
Collinson, Lucie
Kvizhinadze, Giorgi
Nair, Nisha
Foster, Rachel
Dennett, Elizabeth
Sarfati, Diana
Cancer care coordinators in stage III colon cancer: a cost-utility analysis
title Cancer care coordinators in stage III colon cancer: a cost-utility analysis
title_full Cancer care coordinators in stage III colon cancer: a cost-utility analysis
title_fullStr Cancer care coordinators in stage III colon cancer: a cost-utility analysis
title_full_unstemmed Cancer care coordinators in stage III colon cancer: a cost-utility analysis
title_short Cancer care coordinators in stage III colon cancer: a cost-utility analysis
title_sort cancer care coordinators in stage iii colon cancer: a cost-utility analysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523949/
https://www.ncbi.nlm.nih.gov/pubmed/26238996
http://dx.doi.org/10.1186/s12913-015-0970-5
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