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Two cases of hard metal lung disease showing gradual improvement in pulmonary function after avoiding dust exposure
We present herein two cases of hard metal lung disease (HMLD) with distinct pathological findings. Both cases showed gradual improvements in pulmonary function over a period of a few years (Case 1: 30 months; Case 2: 12 months) after the avoidance of dust exposure, while improvements on high-resolut...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524026/ https://www.ncbi.nlm.nih.gov/pubmed/26244050 http://dx.doi.org/10.1186/s12995-015-0070-9 |
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author | Terui, Hiroya Konno, Satoshi Kaga, Kichizo Matsuno, Yoshihiro Hatanaka, Kanako C. Kanno, Hiromi Moriyama, Hiroshi Uo, Motohiro Nishimura, Masaharu |
author_facet | Terui, Hiroya Konno, Satoshi Kaga, Kichizo Matsuno, Yoshihiro Hatanaka, Kanako C. Kanno, Hiromi Moriyama, Hiroshi Uo, Motohiro Nishimura, Masaharu |
author_sort | Terui, Hiroya |
collection | PubMed |
description | We present herein two cases of hard metal lung disease (HMLD) with distinct pathological findings. Both cases showed gradual improvements in pulmonary function over a period of a few years (Case 1: 30 months; Case 2: 12 months) after the avoidance of dust exposure, while improvements on high-resolution computed tomography were modest. The increased lymphocytes and decreased CD4/CD8 ratio in BALF observed at initial diagnosis normalized after the avoidance of dust exposure in one case. To the best of our knowledge, this is the first report demonstrating continual follow-up of pulmonary function and radiographic findings, and a comparison of BALF findings before and after avoidance of hard metal dust exposure. |
format | Online Article Text |
id | pubmed-4524026 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-45240262015-08-05 Two cases of hard metal lung disease showing gradual improvement in pulmonary function after avoiding dust exposure Terui, Hiroya Konno, Satoshi Kaga, Kichizo Matsuno, Yoshihiro Hatanaka, Kanako C. Kanno, Hiromi Moriyama, Hiroshi Uo, Motohiro Nishimura, Masaharu J Occup Med Toxicol Case Report We present herein two cases of hard metal lung disease (HMLD) with distinct pathological findings. Both cases showed gradual improvements in pulmonary function over a period of a few years (Case 1: 30 months; Case 2: 12 months) after the avoidance of dust exposure, while improvements on high-resolution computed tomography were modest. The increased lymphocytes and decreased CD4/CD8 ratio in BALF observed at initial diagnosis normalized after the avoidance of dust exposure in one case. To the best of our knowledge, this is the first report demonstrating continual follow-up of pulmonary function and radiographic findings, and a comparison of BALF findings before and after avoidance of hard metal dust exposure. BioMed Central 2015-08-04 /pmc/articles/PMC4524026/ /pubmed/26244050 http://dx.doi.org/10.1186/s12995-015-0070-9 Text en © Terui et al. 2015 Open Access This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Case Report Terui, Hiroya Konno, Satoshi Kaga, Kichizo Matsuno, Yoshihiro Hatanaka, Kanako C. Kanno, Hiromi Moriyama, Hiroshi Uo, Motohiro Nishimura, Masaharu Two cases of hard metal lung disease showing gradual improvement in pulmonary function after avoiding dust exposure |
title | Two cases of hard metal lung disease showing gradual improvement in pulmonary function after avoiding dust exposure |
title_full | Two cases of hard metal lung disease showing gradual improvement in pulmonary function after avoiding dust exposure |
title_fullStr | Two cases of hard metal lung disease showing gradual improvement in pulmonary function after avoiding dust exposure |
title_full_unstemmed | Two cases of hard metal lung disease showing gradual improvement in pulmonary function after avoiding dust exposure |
title_short | Two cases of hard metal lung disease showing gradual improvement in pulmonary function after avoiding dust exposure |
title_sort | two cases of hard metal lung disease showing gradual improvement in pulmonary function after avoiding dust exposure |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524026/ https://www.ncbi.nlm.nih.gov/pubmed/26244050 http://dx.doi.org/10.1186/s12995-015-0070-9 |
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