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Fetal microglial phenotype in vitro carries memory of prior in vivo exposure to inflammation

Objective: Neuroinflammation in utero may result in life-long neurological disabilities. The molecular mechanisms whereby microglia contribute to this response remain incompletely understood. Methods: Lipopolysaccharide (LPS) or saline were administered intravenously to non-anesthetized chronically...

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Detalles Bibliográficos
Autores principales: Cao, Mingju, Cortes, Marina, Moore, Craig S., Leong, Soo Yuen, Durosier, Lucien D., Burns, Patrick, Fecteau, Gilles, Desrochers, Andre, Auer, Roland N., Barreiro, Luis B., Antel, Jack P., Frasch, Martin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524165/
https://www.ncbi.nlm.nih.gov/pubmed/26300730
http://dx.doi.org/10.3389/fncel.2015.00294