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Fetal microglial phenotype in vitro carries memory of prior in vivo exposure to inflammation
Objective: Neuroinflammation in utero may result in life-long neurological disabilities. The molecular mechanisms whereby microglia contribute to this response remain incompletely understood. Methods: Lipopolysaccharide (LPS) or saline were administered intravenously to non-anesthetized chronically...
Autores principales: | Cao, Mingju, Cortes, Marina, Moore, Craig S., Leong, Soo Yuen, Durosier, Lucien D., Burns, Patrick, Fecteau, Gilles, Desrochers, Andre, Auer, Roland N., Barreiro, Luis B., Antel, Jack P., Frasch, Martin G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524165/ https://www.ncbi.nlm.nih.gov/pubmed/26300730 http://dx.doi.org/10.3389/fncel.2015.00294 |
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