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Pachymic acid induces apoptosis via activating ROS-dependent JNK and ER stress pathways in lung cancer cells

BACKGROUND: Pachymic acid (PA), a lanostane-type triterpenoid from Poria cocos, has been reported to possess anti-emetic, anti-inflammatory, and anti-cancer properties. Nonetheless, the anti-tumor effect of PA in lung cancer cells remains unclear. Herein, we report the chemotherapeutic effects and u...

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Detalles Bibliográficos
Autores principales:	Ma, Jun, Liu, Jun, Lu, Chunwei, Cai, Dingfang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524283/ https://www.ncbi.nlm.nih.gov/pubmed/26244039 http://dx.doi.org/10.1186/s12935-015-0230-0

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