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Hot spots of DNA double-strand breaks and genomic contacts of human rDNA units are involved in epigenetic regulation

DNA double-strand breaks (DSBs) are involved in many cellular mechanisms, including replication, transcription, and genome rearrangements. The recent observation that hot spots of DSBs in human chromosomes delimit DNA domains that possess coordinately expressed genes suggests a strong relationship b...

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Detalles Bibliográficos
Autores principales:	Tchurikov, Nickolai A., Fedoseeva, Daria M., Sosin, Dmitri V., Snezhkina, Anastasia V., Melnikova, Nataliya V., Kudryavtseva, Anna V., Kravatsky, Yuri V., Kretova, Olga V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524424/ https://www.ncbi.nlm.nih.gov/pubmed/25280477 http://dx.doi.org/10.1093/jmcb/mju038

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