Epigenome-wide association study reveals decreased average methylation levels years before breast cancer diagnosis

BACKGROUND: Interest in the potential of DNA methylation in peripheral blood as a biomarker of cancer risk is increasing. We aimed to assess whether epigenome-wide DNA methylation measured in peripheral blood samples obtained before onset of the disease is associated with increased risk of breast ca...

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Detalles Bibliográficos
Autores principales: van Veldhoven, Karin, Polidoro, Silvia, Baglietto, Laura, Severi, Gianluca, Sacerdote, Carlotta, Panico, Salvatore, Mattiello, Amalia, Palli, Domenico, Masala, Giovanna, Krogh, Vittorio, Agnoli, Claudia, Tumino, Rosario, Frasca, Graziella, Flower, Kirsty, Curry, Ed, Orr, Nicholas, Tomczyk, Katarzyna, Jones, Michael E., Ashworth, Alan, Swerdlow, Anthony, Chadeau-Hyam, Marc, Lund, Eiliv, Garcia-Closas, Montserrat, Sandanger, Torkjel M., Flanagan, James M., Vineis, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524428/
https://www.ncbi.nlm.nih.gov/pubmed/26244061
http://dx.doi.org/10.1186/s13148-015-0104-2

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