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Epigenome-wide and transcriptome-wide analyses reveal gestational diabetes is associated with alterations in the human leukocyte antigen complex

BACKGROUND: Gestational diabetes mellitus (GDM) affects approximately 10 % of pregnancies in the United States and increases the risk of adverse health outcomes in the offspring. These adult disease propensities may be set by anatomical and molecular alterations in the placenta associated with GDM....

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Detalles Bibliográficos
Autores principales: Binder, Alexandra M., LaRocca, Jessica, Lesseur, Corina, Marsit, Carmen J., Michels, Karin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524439/
https://www.ncbi.nlm.nih.gov/pubmed/26244062
http://dx.doi.org/10.1186/s13148-015-0116-y