Sustained co-delivery of BIO and IGF-1 by a novel hybrid hydrogel system to stimulate endogenous cardiac repair in myocardial infarcted rat hearts

Dedifferentiation and proliferation of endogenous cardiomyocytes in situ can effectively improve cardiac repair following myocardial infarction (MI). 6-Bromoindirubin-3-oxime (BIO) and insulin-like growth factor 1 (IGF-1) are two potent factors that promote cardiomyocyte survival and proliferation....

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Detalles Bibliográficos
Autores principales: Fang, Rui, Qiao, Shupei, Liu, Yi, Meng, Qingyuan, Chen, Xiongbiao, Song, Bing, Hou, Xiaolu, Tian, Weiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524466/
https://www.ncbi.nlm.nih.gov/pubmed/26251592
http://dx.doi.org/10.2147/IJN.S81451

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