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Genetic association between G protein-coupled receptor kinase 6/β-arrestin 2 and dopamine supersensitivity psychosis in schizophrenia
BACKGROUND/AIM: Dopamine supersensitivity psychosis (DSP), clinically characterized by unstable and severe psychosis or tardive dyskinesia and often categorized as treatment-resistant schizophrenia, is promoted by long-term antipsychotic treatment. An upregulation of the dopamine D(2) receptor cause...
Autores principales: | Oda, Yasunori, Kanahara, Nobuhisa, Kimura, Hiroshi, Watanabe, Hiroyuki, Hashimoto, Kenji, Iyo, Masaomi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524575/ https://www.ncbi.nlm.nih.gov/pubmed/26251601 http://dx.doi.org/10.2147/NDT.S86042 |
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