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Tumor Progression Locus 2 Promotes Induction of IFNλ, Interferon Stimulated Genes and Antigen-Specific CD8(+) T Cell Responses and Protects against Influenza Virus
Mitogen-activated protein kinase (MAP) cascades are important in antiviral immunity through their regulation of interferon (IFN) production as well as virus replication. Although the serine-threonine MAP kinase tumor progression locus 2 (Tpl2/MAP3K8) has been implicated as a key regulator of Type I...
Autores principales: | Kuriakose, Teneema, Tripp, Ralph A., Watford, Wendy T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524623/ https://www.ncbi.nlm.nih.gov/pubmed/26241898 http://dx.doi.org/10.1371/journal.ppat.1005038 |
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