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Retrohoming of a Mobile Group II Intron in Human Cells Suggests How Eukaryotes Limit Group II Intron Proliferation

Mobile bacterial group II introns are evolutionary ancestors of spliceosomal introns and retroelements in eukaryotes. They consist of an autocatalytic intron RNA (a “ribozyme”) and an intron-encoded reverse transcriptase, which function together to promote intron integration into new DNA sites by a...

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Detalles Bibliográficos
Autores principales:	Truong, David M., Hewitt, F. Curtis, Hanson, Joseph H., Cui, Xiaoxia, Lambowitz, Alan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524724/ https://www.ncbi.nlm.nih.gov/pubmed/26241656 http://dx.doi.org/10.1371/journal.pgen.1005422

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