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The Nucleosome Acidic Patch Regulates the H2B K123 Monoubiquitylation Cascade and Transcription Elongation in Saccharomyces cerevisiae

Eukaryotes regulate gene expression and other nuclear processes through the posttranslational modification of histones. In S. cerevisiae, the mono-ubiquitylation of histone H2B on lysine 123 (H2B K123ub) affects nucleosome stability, broadly influences gene expression and other DNA-templated process...

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Detalles Bibliográficos
Autores principales: Cucinotta, Christine E., Young, Alexandria N., Klucevsek, Kristin M., Arndt, Karen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524731/
https://www.ncbi.nlm.nih.gov/pubmed/26241481
http://dx.doi.org/10.1371/journal.pgen.1005420